Laboratory/Research Associate-Protein Purification
Cleveland, OH 

Objectives:  Assist in the purification of insulin analogs and precursors from microbial and synthetic sources

Reports to:  Managing Scientist-Protein Purification


  • Purify novel insulins and their precursors using established protocols
  • Characterize novel insulins using reverse-phase (RP) analytical chromatography, mass spectrometry and various other biochemical methods
  • Develop new purification schemes for insulin analogs
  • Optimize procedures and protocols to improve yield, throughput and purity
  • Perform laboratory tasks safely, rapidly, and efficiently
  • Report results in written and verbal format
  • Record results accurately and meticulously

Typical activities:

  • Perform analytical and preparative scale RP-HPLC purification
  • Perform chromatography in column and batch mode including: HIC, SEC, IEX
  • Assist in the design of protein purification techniques
  • Continue to improve  method to increase yield, efficiency and scale
  • Characterize insulin molecules using a variety of techniques including RP-U/HPLC, mass spectrometry, and peptide mapping
  • Report progress in summary and detail on a regular basis to colleagues and supervisors
  • Keep accurate laboratory notebooks


  • Excellent “hands” in executing laboratory methods, particularly handling proteins
  • Experience using analytical HPLC, preferably reverse phase
  • Data driven decision-maker
  • Excellent project planning and time management abilities
  • Good listener.  Strong, concise, and consistent written and oral communication

Personal characteristics:

  • Meticulous and detail oriented, responsible & mature
  • Innovative thinker
  • Passionate, committed to excellence; driven to make projects and company succeed
  • Persistent/tenacious, proactive self-starter, thorough follow-up; problem solver
  • Initiates change. Sense of urgency.
  • Takes responsibility. Gets things done personally as well as through others
  • Risk taker; flexible and adaptable.  Comfortable with ambiguity.
  • Collaborative; team player; sense of humor
  • Demonstrated strong ethics


  • At least 1 year experience post graduation, preferably in an industry setting
  • At least 3 distinct, observable examples where achieved meaningful excellence
  • Must have an M.S in biochemistry or related science in addition to appropriate laboratory experience

Candidates should apply to:

We do not provide sponsorship. Must be eligible to work in the US.

Compensation:  We offer competitive salary, incentive stock options and bonus based on agreed upon milestones